Click on Mouse and TrackPad followed by ‘Enable Access for Assistive Devices.’ Now open up Finder on your Mac and look up ‘Apple Script’. How to Make a Clicker on your Mac without any external Download (Trick) Go to System Preferences and click on Universal Access. Even though we can also use the Web Browser plugin for the automation as well. Or even can create our own by using the free tool called AutoHotKey (requires some knowledge of programming). Either we can use the already program tools called Auto Clickers. Now there are several ways that can be used to make mouse click automatically.